Diana Goode and Andrew Douglas are a California couple who seem to have it all, and after their wedding, Diana teases that she will make a baby on their honeymoon. But long afterwards, she is still not pregnant. As they wait out each month with anticipation, only to be disappointed, they are forced to question just how much they are willing to go through to have a baby, and at what cost to their marriage. Charlie Winwood, having grown up as an orphan, dreams of a house filled with children, but his bride -- fun seeking actress Barbie Mason -- has other ideas. Their marriage is strained, but Charlie is convinced a baby will solve it all. Pilar Graham, a prominent attorney in her early forties, astonishes her friends by marrying Judge Brad Coleman, a man in his sixties and the father of two grown children. Pilar begins to wonder if some day she will regret not having a baby with Brad, but it will not be easy for them as they encounter the world of high-tech medicine and the bittersweet rewards it brings.
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